Stem cells in the brain will differentiate into brain cells to repair damage. But Japanese researchers found that many of the brain cells so differentiated are often abandoned halfway and stop developing, making it difficult to restore brain function. As a result, they injected a beneficial protein into brain-damaged mice in animal experiments. As a result, the damaged brain cells of the mice recovered significantly.
Comprehensive foreign news reported on the 21st that the research team led by Professors Sawamoto and Yan of Nagoya City University completed the above research, and it was a glial cell that was successfully regenerated. The function of such cells is to protect brain nerve cells and provide them with nutrients. Periventricular white matter softening (PVL), which can cause cerebral palsy in children, is caused by decreased cerebral blood flow and insufficient oxygen supply, which in turn leads to the death of this glial cell.
There are stem cells in the brain that can differentiate into glial cells. If the glial cells die, the stem cells will differentiate into new cells. However, researchers such as Sawamoto and Yan analyzed brain-damaged mice and monkeys and found that most of these newly differentiated cells stopped growing and developing. Because new cells mostly stay in immature state, the brain function of mice and monkeys It is difficult to recover.
The researchers then injected a growth-promoting protein into mice with periventricular leukoaraiosis. As a result, immature neonatal glial cells in the mouse brain continued to develop, and the mature cells eventually developed more than those without the growth-promoting protein In the case of about 50% more.
Zeben Heyan pointed out that this achievement is expected to be used to develop new treatments for diseases such as cerebral palsy and cerebral infarction. In addition, repairing damaged brain cells with induced multifunctional stem cells (iPS cells) is one of the current hot topics in regenerative medicine. When performing such repairs, iPS cells must be differentiated into brain cells, and then undifferentiated mature brain cells can be transplanted into animal brains to allow them to mature naturally in the body.
Cotton Pads,Embossed Cotton Pads,Cotton Round,Pure Cotton Rounds
COTTONWHISPER (TAIZHOU) DAILY PRODUCTS CO.,LTD , https://www.zjcosmeticpuff.com